Upcycle: Edit/delete of units
I didn't see how to edit or delete units. Maybe the same for resource specifications? In the case of units, seems like delete is probably enough, easy to re-add, unless that messes up some internal key.
upcycle offer: lost other info after uploading image
I filled out an offer, then uploaded a picture, after it uploaded, what I had filled out was gone, had to re-enter before saving offer.
Unknown type of activity/object
Discussion: Switches the user from upcycle to other flavours?
Why does it switch you into another flavour? It is confusing as someone who assumes they are doing one thing here, feels like we should stay in Upcycle. Or somehow automatically come back.
tech - trying out GNU/Linux distributions on my new laptop
Solus seems to work great, the only issues I went through were related to the command line interface (vim wasn’t installed, and only available through eopkg, not through the GUI packages installer, and doas isn’t ported yet), which isn’t a problem given its graphical focus (conversely to Alpine Linux which focuses on the CLI experience first).
texstudio and rstudio are both available through the graphical packages installer so let’s see how this turns out…
tech - trying out GNU/Linux distributions on my new laptop - bug report
So far, the Solus installer stays on a Qwerty layout, but does perform the mkinitcpio hooks that turn the keyboard at the FDE password time into an alternative layout (e.g. Dvorak) on the second boot, which means that instead of not working on the first boot, it doesn’t on the later ones (which isn’t ideal if you use a YubiKey, or at all really).
As usual I’ve worked around this problem by setting a Qwerty layout at install time, and changing it after rebooting.
When I need to enter my password to unlock my session, the layout stays on Qwerty, which isn’t elegant… Because there’s FDE anyway, I’ll just try to remove this prompt.
tech - trying out GNU/Linux distributions on my new laptop
Solus seems to work great, the only issues I went through were related to the command line interface (vim wasn’t installed, and only available through eopkg, not through the GUI packages installer, and doas isn’t ported yet), which isn’t a problem given its graphical focus (conversely to Alpine Linux which focuses on the CLI experience first).
texstudio and rstudio are both available through the graphical packages installer so let’s see how this turns out…
I'm new here, finally after months I was able to receive the confirmation mail...
For now, I'll just copy one thing I wrote on Mastodon and to see how it works.
#Medicine #pharmaceutical #explanation
Some information about how new medicines are made by a guy who read a bit about it.
Most medicines target a particular protein in the human body.
The objective is to have something that interacts with the protein so that the function of the protein is altered.
Many things can be used to alter those mechanisms, such as small molecules, other proteins, antibodies and other things.
These things hopefully go nearby the protein of interest and modify its shape or block some part of it.
It is difficult to find one such thing that modifies the function of the protein in the desired way that is expected to cure the disease.
It's even more difficult to find one who does not interact with other proteins and causes toxic side effects.
I'll quickly outline some methodologies used to find small molecules that can act as medicines.
Small molecules are molecules made up of atoms with a contained dimension, much smaller than the common protein.
One very simple way to find such a molecule is to test a lot of different molecules with the protein in a laboratory and observing if something good happens.
This methodology is pretty good since it requires no prior knowledge about the protein nor about the molecules you're testing.
This procedure however also has some downsides: you need to obtain all the molecules you need to test and you need either a lot of people testing them or some specialized machinery.
This is of course very expensive.
Moreover, if none of the molecules you were able to obtain are good for curing the disease, you just spent a lot of money and gained little information about how to cure the disease.
This first methodology is very widespread in the big pharma industry, since they have the means to sustain the costs of a potentially fruitless expense.
It is difficult to find this kind of methodologies used in universities and research institutions, due to more limited budget.
Alright, this was a first quick introduction to the theme, if you're interested I can write a bit more; trying to keep it simple.
Let me know what you could be interested in knowing.
Hi, late reply but thank you for this message, it’s very interesting. What’s a protein?
If the title is too long, it breaks the menu
I put a content warning in the previous message by mistake, i don't know how to edit my reply to remove it
It highlights the reply you clicked from the feed. Given we visualise threads with a nested UI, users may need a visual reference of where they are when they click to a reply from a timeline (but i agree that's not clear at all)